Most of us associate high Histamine with hay fever, hives and a runny nose. Did you know that Histamine is naturally occurring in our body and food? Histamine is influenced by our Gut health, Immune system, Brain (affects neurotransmitters), Inflammation and of course foods high in histamine. Anti-histamines do fix the symptoms but if you want to treat the cause it is balancing digestive enzymes, boosting immune function and reducing inflammation.